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Top 5 Cosmetic Products for Forehead Creases

By November 8, 2020August 4th, 2022Forehead

Forehead creases, or forehead wrinkles, are a common complaint among people in dermatology. They develop due to several reasons like increased use of facial muscles, or age-related, loss of skin elasticity. Whatever the reason may be, they can be easily treated using various topical agents or injectable fillers.

However, there is an overwhelming number of products available for the removal of forehead wrinkles, and finding ‘the one’ for yourself can be a long and tedious process. But worry no more. We have done the work for you and chosen the five best products to reduce forehead creases!

Read our in-depth article on what forehead wrinkles are; their causes, prevention and surgical treatment here. Image appropriated from Kang, S. M., Feneran, A., Kim, J. K., Park, O., Kim, J. E., Won, C. H., … Lee, S. H. (2011). (16)

1. La Prairie Anti-Aging Rapid Response Booster

$630 USD on Amazon

Value For Money


  • Reduces depth and length of wrinkles
  • Helps control the evolution of skin aging
  • Exfoliates to refine skin and minimize the look of imperfections


  • It may not work for some users

The La Prairie anti-aging rapid response booster is a luxurious line correcting serum that guarantees smooth and young-looking skin with just 15 days of use. The wrinkle-filling serum is a potent blend of L-arginine, Glycyrrhiza Glabra (Licorice) Root Extract, Morus Alba Root Extract, and Scutellaria Baicalensis Root Extract.

The key ingredients work together to hydrate and moisturize the skin while also smoothening it by removing any fine lines or wrinkles that may be present. L-arginine, semi-essential amino acid and a fundamental ingredient is crucial for skin repair and wound healing process, which in turn enhance collagen synthesis in the skin (1). Collagen is important for the tightening of the skin and is responsible for maintaining the integrity of the skin (2).

Another important ingredient is the phytoextract of Morus Alba Root which is known for its anti-oxidant properties, which are important for protection from photodamage (3). Photodamage or UV exposure can age the skin significantly and increase the appearance of wrinkles. The flavinoids in Morus alba root extract prevent this damage by quenching the reactive species formed as a result of UV damage (3).

The Scutellaria baicalensis root extract further enhances the effects of other ingredients by acting as a natural UV protectant for the human skin, releasing anti-oxidants to reverse the effects of photoaging (4).

Basically, this product is a luxurious blend of natural ingredients that will make your skin look young and refreshed for days.

2. Erasa Xep 30 Extreme Line Lifting and Rejuvenation Concentrate

$160 USD on Amazon

Value For Money


  • Reduces fine lines and wrinkles
  • Can be used under makeup
  • Quick results


  • Might leave your skin dry
  • Harsh on sensitive skin

The Erasa Xep 30 Extreme Line Lifting and Rejuvenation Concentrate is a revolutionary product that is designed to mimic snail cone venom to smoothen the skin and erase all signs of aging. Unlike creams and lotions, it produces results with just one-time use.

This cruelty-free and paraben-free product is a strong concoction of the XEP 30 neuropeptide with Sodium hyaluronate, creatine, and niacinamide. The XEP 30 neuropeptide is combined with other, similar neuropeptides to form the ultimate, award-winning Erasa peptide that diminishes the signs of aging significantly.

Niacinamide, a B vitamin, is a strong and potent ingredient in skincare products. In fact, a double-blind, randomized clinical trial following 50 female subjects observed several beneficial effects of the vitamin, especially in anti-aging processes (5).
It significantly reduces the wrinkles and fine lines on the face along with hyperpigmented spots which are common signs of aging skin while also improving skin elasticity to prevent age-related sagging of the facial skin (5).

Creatine is another important ingredient of the product that works on the dermal density and improves skin elasticity and significantly reduces the free radical production in the skin that can age the skin remarkably (6).

Overall, all ingredients work together to tighten, brighten, and rejuvenate the skin to give your face a youthful glow like never seen before.

3. Estée Lauder Perfectionist Pro Rapid Firm + Lift Treatment

$55 USD on Amazon

Value For Money


  • Quick firming and lifting results
  • Softens the look of fine lines and wrinkles
  • Makes skin radiant and corrects uneven skin texture and tone


  • Requires continuous application of sunscreen as long as you are using this serum because of AHAs
  • Contains undesirable ingredients like PEGs and phenoxyethanol
  • Expensive

The Estée Lauder Perfectionist Pro Rapid Firm + Lift Treatment is a fast-acting serum that works on reducing the size of your pores and the fine lines on your face, while also tightening the skin to give it a firm and sleek look. This anti-acnegenic product is a beautiful marriage of caffeine, algae extract, sodium hyaluronate, and linoleic acid that works to give your skin a plump and hydrated look.

Caffeine is widely used in the production of skincare products due to its ability to penetrate the skin barrier and improving the microcirculation in the skin which visibly smoothens and refreshes the skin (7). Moreover, caffeine slows down the effects of UV damage on the skin and protects the skin from oxidative stress which is responsible for the premature aging of the skin (8).

Sodium hyaluronate, a sodium salt of hyaluronic acid, improves the wound healing properties of the skin, indirectly increasing collagen synthesis in the skin (9). Reduced collagen is one of the main reasons for the aging of the skin and the increase in collagen by sodium hyaluronate can significantly improve the appearance of the skin (10).

Basically, this product targets all of the effects of aging on the skin and diminishes them remarkably, making your skin firm and refreshed.

4. Kate Somerville 2-in-1 Plumping Moisturizer + Serum

$98 USD on Amazon

Value For Money


  • Improves skin elasticity
  • Reduces fine lines and wrinkles
  • Hydrates skin deeply


  • Uncomfortable on some skin types
  • Not recommended for some skin types
  • Quite expensive

The Kate Somerville 2-in-1 Plumping Moisturizer + Serum is a multitasking serum that works as an anti-aging agent, a makeup primer, and a moisturizer for your skin. The product guarantees instant results with Kate’s clinic claiming that the Wrinkle Warrior can visibly soothe wrinkles within thirty minutes of use. This clinically perfected, the fast-absorbing product is a potent blend of age-conquering hydrolyzed hyaluronic acid, Sodium hyaluronate, Sichuan peppers, and glucosamine.

Glucosamine compounds are widely used in cosmetic care products due to their ability to stimulate hyaluronic acid synthesis (11). Hyaluronic acid has strong anti-inflammatory, anti-aging, anti-wrinkle properties that make it crucial for hydration and rejuvenation of the skin (12).

The use of sodium hyaluronate, hyaluronic acid, and glucosamine compounds together guarantee instant hydration of the skin and would explain the ‘results within thirty minutes of use’ claim made by Kate’s Clinic. All these potent ingredients work together to reduce the fine lines and wrinkles while also increasing the collagen content of the skin to prevent any further damage to the skin by aging.

5. Strivectin Wrinkle Recode Line Transforming Melting Serum

$63 USD on Amazon

Value For Money


  • Rich in skin-replenishing emollients that diminish the look of wrinkles
  • Lush, protective texture helps prevent moisture loss
  • Contains a form of niacinamide and a peptide


  • Not as rich in proven anti-aging ingredients as less expensive serums
  • Contains fragrance ingredients that pose a risk of irritation
  • Contains a little-known plant oil from the rose family that could be a problem for skin

The Strivectin Wrinkle Recode Line Transforming Melting Serum is a super-concentrated, high-tech melting blend of Calendula officinalis extract, Prinsepia Utilis Seed Oil, Myristyl Nicotinate, Macadamia Integrifolia Seed Oil, and BHT.

The StriVectin brand prides itself on providing consumers with targeted solutions to all aging-related skin problems and this product is a testimony of that. The Calendula officinalis flower extract is a product of traditional medicine and is often used to heal skin ulcers and burns(13). The wound healing properties of the flower make it a vital ingredient in skincare products. The use of Prinsepia Utilis Seed Oil extract is associated with an improved skin barrier that hydrates the skin and prevents transepidermal water loss which can have a significantly negative impact on the skin texture (14).

The skin barrier is further enhanced by the use of myristyl nicotinamide, a derivative of niacin that targets photodamaged skin to reverse and prevent any further damage(15). Overall, all ingredients in this smooth blend work together to improve the skin texture and smoothen the skin to give it a radiant, spry glow.


  1. Kocic, H et al. “Proliferative, anti-apoptotic and immune-enhancing effects of L-arginine in culture of skin fibroblasts.” Journal of biological regulators and homeostatic agents vol. 31,3 (2017): 667-672.
  2. Bainbridge P. Wound healing and the role of fibroblasts. J Wound Care. 2013 Aug;22(8):407-8, 410-12. doi: 10.12968/jowc.2013.22.8.407. PMID: 23924840.
  3. Jadoon, Saima et al. “Anti-Aging Potential of Phytoextract Loaded-Pharmaceutical Creams for Human Skin Cell Longetivity.” Oxidative medicine and cellular longevity vol. 2015 (2015): 709628. doi:10.1155/2015/709628
  4. Seok, Jin Kyung et al. “Scutellaria radix Extract as a Natural UV Protectant for Human Skin.” Phytotherapy research : PTR vol. 30,3 (2016): 374-9. doi:10.1002/ptr.5534
  5. Bissett, Donald L et al. “Niacinamide: A B vitamin that improves aging facial skin appearance.” Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] vol. 31,7 Pt 2 (2005): 860-5; discussion 865. doi:10.1111/j.1524-4725.2005.31732
  6. Sanz, Maria Teresa et al. “Biorevitalizing effect of a novel facial serum containing apple stem cell extract, pro-collagen lipopeptide, creatine, and urea on skin aging signs.” Journal of cosmetic dermatology vol. 15,1 (2016): 24-30. doi:10.1111/jocd.12173
  7. Herman, A, and A P Herman. “Caffeine’s mechanisms of action and its cosmetic use.” Skin pharmacology and physiology vol. 26,1 (2013): 8-14. doi:10.1159/000343174
  8. Li, Yi-Fang et al. “Caffeine Protects Skin from Oxidative Stress-Induced Senescence through the Activation of Autophagy.” Theranostics vol. 8,20 5713-5730. 10 Nov. 2018, doi:10.7150/thno.28778
  9. Bukhari, Syed Nasir Abbas et al. “Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects.” International journal of biological macromolecules vol. 120,Pt B (2018): 1682-1695. doi:10.1016/j.ijbiomac.2018.09.188
  10. Varani, James et al. “Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation.” The American journal of pathology vol. 168,6 (2006): 1861-8. doi:10.2353/ajpath.2006.051302
  11. Bissett, Donald L. “Glucosamine: an ingredient with skin and other benefits.” Journal of cosmetic dermatology vol. 5,4 (2006): 309-15. doi:10.1111/j.1473-2165.2006.00277.x
  12. Bukhari, Syed Nasir Abbas et al. “Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects.” International journal of biological macromolecules vol. 120,Pt B (2018): 1682-1695. doi:10.1016/j.ijbiomac.2018.09.188
  13. Givol, Or et al. “A systematic review of Calendula officinalis extract for wound healing.” Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society vol. 27,5 (2019): 548-561. doi:10.1111/wrr.12737
  14. Wang, Yinjuan et al. “Assessment of the efficacy of a new complex antisensitive skin cream.” Journal of cosmetic dermatology vol. 17,6 (2018): 1101-1107. doi:10.1111/jocd.12486
  15. Jacobson, Myron K et al. “Effect of myristyl nicotinate on retinoic acid therapy for facial photodamage.” Experimental dermatology vol. 16,11 (2007): 927-35. doi:10.1111/j.1600-0625.2007.00616.x
  16. Kang SM, Feneran A, Kim JK, et al. Exaggeration of wrinkles after botulinum toxin injection for forehead horizontal lines. Ann Dermatol. 2011;23(2):217-221. doi:10.5021/ad.2011.23.2.217
Dr Mingma Sony

Mingma Sony MD is a medical practitioner currently working hard to provide health-related services to people in need. With a medical degree completed at a young age, she is also a valued medical writer and editor at QOVES Studio. She writes medical articles with impeccable accuracy owing to her vast medical knowledge and thorough research.